Severe reactions to a brown recluse spider bite Your doctor will consider other potential culprits of your symptoms, like another type of insect bite or a separate skin condition. If the wound hasn’t responded to treatment or symptoms don’t align with the typical presentation of a brown recluse bite, it may be time for a differential diagnosis. Surgery may be required to remove or repair excess dead tissue. If tissue death continues to occur or has already affected a large area, you’ll need to be evaluated by a surgeon. In very rare cases where a lot of venom was delivered, necrosis in the wound can extend beyond the skin and into the muscles. Most brown recluse bites will heal fully, without complications, in 3 months or less. This looks like a big, black scab covering the wound area. The site of the wound may start to develop necrotic (dead) tissue called eschar.
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